The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2009
Filed:
Jan. 28, 2005
Asa Rosenquist, Huddinge, SE;
Fredrik Thorstensson, Linkoping, SE;
Per-ola Johansson, Linkoping, SE;
Ingemar Kvarnstrom, Linkoping, SE;
Susana Ayesa, Huddinge, SE;
Bjorn Classon, Huddinge, SE;
Laszlo Rakos, Huddinge, SE;
Bertil Samuelsson, Huddinge, SE;
Asa Rosenquist, Huddinge, SE;
Fredrik Thorstensson, Linkoping, SE;
Per-Ola Johansson, Linkoping, SE;
Ingemar Kvarnstrom, Linkoping, SE;
Susana Ayesa, Huddinge, SE;
Bjorn Classon, Huddinge, SE;
Laszlo Rakos, Huddinge, SE;
Bertil Samuelsson, Huddinge, SE;
Medivir AB, Huddinge, SE;
Abstract
Compounds of the formula where the variables are as defined in the specification inhibit the NS3 protease of flavivirus such as hepatitis C virus (HCV). The compounds comprise a novel linkage between a heterocyclic P2 unit and those portions of the inhibitor more distal to the nominal cleavage site of the native substrate, which linkage reverses the orientation of peptidic bonds on the distal side relative to those proximal to the cleavage site.