Company Filing History:
Years Active: 1997-1998
Title: The Innovative Contributions of Per Klemm
Introduction
Per Klemm is a notable inventor based in Frederiksberg, Denmark. He has made significant contributions to the field of biotechnology, particularly in the area of immunization and biological containment. With a total of 3 patents to his name, Klemm's work has the potential to impact both medical and industrial applications.
Latest Patents
Klemm's latest patents include a method of immunization using biologically contained bacterial cells. This innovative approach involves immunizing a vertebrate animal, such as a human, with a bacterial host cell that harbors a recombinant replicon. This replicon provides a stochastically expressed cell killing function, ensuring that the cells are biologically contained. Additionally, the replicon comprises a gene encoding an antigen that is displayed on the outer surface of the host cell, eliciting an immune response from the immunized animal. The antigen includes one or more epitopes from a pathogenic agent.
Another significant patent focuses on biological containment. This involves a replicon in which a nucleotide sequence encoding a cell killing function is expressed when harbored in a primary host cell. Under specific conditions, cells harboring the replicon are killed, while in a secondary host cell, the nucleotide sequence can be expressed either constitutively or regulatably. This principle can be utilized in the industrial production of biosynthetic products through recombinant DNA techniques, particularly when releasing genetically engineered microorganisms into the environment or preparing live vaccines.
Career Highlights
Throughout his career, Per Klemm has worked with several companies, including Gx Biosystems A/S and Genexpress ApS. His experience in these organizations has contributed to his expertise in biotechnology and patent development.
Collaborations
Klemm has collaborated with notable individuals in his field, including So Slashedren Molin and Poul Kirketerp Andersson. These collaborations have likely enriched his research and innovation efforts.
Conclusion
Per Klemm's innovative work in biotechnology, particularly in immunization and biological containment, showcases his significant contributions to the field. His patents reflect a commitment to advancing medical and industrial applications through scientific research and collaboration.