Company Filing History:
Years Active: 2006-2014
Title: Innovations by Per E Nielsen
Introduction
Per E Nielsen is a notable inventor based in Westlake, OH (US). He has made significant contributions to the field of permeability assays and physicochemical property testing. With a total of 3 patents, his work has advanced the understanding and application of molecular permeability.
Latest Patents
One of his latest patents is a permeation device and method for reducing aqueous boundary layer thicknesses. This invention provides a permeation device comprising a receiving vessel with an aperture adapted for receiving an insert well. Both the vessel and well can be used as donor or acceptor compartments for permeability assays. The device includes a porous support that may consist of biological or biomimetic materials, allowing a molecular entity to permeate through it. In one embodiment, a stirring member disposed in the vessel can provide solution agitation to reduce aqueous boundary layer thickness adjacent to the support. This innovation can reduce boundary layer thicknesses to less than about 15 micrometers, closely approximating in vivo absorption and transport conditions.
Another significant patent involves methods and systems for in situ physicochemical property testing. This apparatus evaluates physicochemical properties of sample materials contained in an array of vessels. It includes a light detector and a light source for transmitting a light beam through the sample material to the detector. An analyzer processes data from the light detector to determine concentration-related properties of the sample material over time. The mixing system features multiple magnetic stirrer elements and an array of magnetic drive elements, allowing simultaneous movement of each magnetic drive element relative to its associated vessel.
Career Highlights
Per E Nielsen is currently associated with Pion Inc., where he continues to innovate and develop new technologies. His work has been instrumental in enhancing the efficiency and accuracy of permeability assays and physicochemical testing.
Collaborations
He has collaborated with notable coworkers, including Alex Avdeef and Chau M Du, contributing to advancements in their respective fields.
Conclusion
Per E Nielsen's contributions to the field of permeability and physicochemical testing are noteworthy. His innovative patents reflect his commitment to advancing scientific understanding and practical applications.