Helsingborg, Sweden

Per Axel Björk


Average Co-Inventor Count = 5.8

ph-index = 2

Forward Citations = 71(Granted Patents)


Company Filing History:


Years Active: 2003

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2 patents (USPTO):Explore Patents

Title: Per Axel Björk: Innovator in Immunomodulating Compounds

Introduction

Per Axel Björk is a notable inventor based in Helsingborg, Sweden. He has made significant contributions to the field of immunology through his innovative research and development of novel compounds. With a total of two patents to his name, Björk's work focuses on advancing medical treatments for various conditions.

Latest Patents

Björk's latest patents include groundbreaking work on immunomodulating compounds. The present invention relates to a novel heterocyclic compound and a pharmaceutical composition comprising said compound. This invention is aimed at clinical treatment for medical conditions that may benefit from immunomodulation, such as rheumatoid arthritis, multiple sclerosis, diabetes, asthma, transplantation, systemic lupus erythematosus, and psoriasis. More specifically, the invention involves CD80 antagonists capable of inhibiting interactions between CD80 and CD28. Additionally, a method for screening compounds that inhibit ligand-induced co-stimulatory receptor internalization pathways in immune-competent human cells is described. This method includes incubating immune-competent human cells under conditions that induce co-stimulatory receptor internalization in the presence of at least one test compound. The suppression of ligand-induced co-stimulatory receptor internalization is then determined. Furthermore, the patent describes a kit for use in this method, as well as an immunoregulatory drug that can block down-modulation of a ligand-induced receptor.

Career Highlights

Throughout his career, Per Axel Björk has worked with prominent companies in the pharmaceutical industry, including Pharmacia AB and Active Biotech AB. His experience in these organizations has contributed to his expertise in developing innovative medical solutions.

Collaborations

Björk has collaborated with notable colleagues in his field, including Per Antonsson and Mikael Dohlsten. These collaborations have further enhanced his research and development efforts.

Conclusion

Per Axel Björk is a distinguished inventor whose work in immunomodulating compounds has the potential to significantly impact the treatment of various medical conditions. His innovative patents and collaborations reflect his commitment to advancing healthcare solutions.

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