This inventor holds 1 USPTO granted patent and 1 published patent application. Top assignees: H. Lee Moffitt Cancer Center and Research Institute, Inc., University of South Florida. Active years: 2025.
Company Filing History:
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1 out of 1,984 
Years Active: 2025
Title: The Innovative Contributions of Peng Sang
Introduction
Peng Sang is a notable inventor based in Tampa, Florida. He has made significant strides in the field of cancer research through his innovative work on protein-protein interactions. His contributions are particularly focused on developing therapeutic agents that can disrupt harmful interactions in cancer cells.
Latest Patents
Peng Sang holds a patent for "B-catenin/B-cell Lymphoma 9 protein-protein interaction inhibiting peptidomimetics." This patent discloses a series of helical sulfono-γ-AApeptides that mimic the binding mode of the α-helical HD2 domain of B-Cell Lymphoma 9 (BCL9). These sulfono-γ-AApeptides can structurally and functionally mimic the α-helical domain of BCL9, selectively disrupting β-catenin/BCL9 protein-protein interactions (PPIs) with higher potency. Remarkably, these peptides can enter cancer cells, bind with β-catenin, and exhibit excellent cellular activity, proving to be much more potent than the BCL9 peptide. Furthermore, enzymatic stability studies have demonstrated the remarkable stability of these helical sulfono-γ-AApeptides, showing no degradation in the presence of pronase for 24 hours, which enhances their biological potential.
Career Highlights
Throughout his career, Peng Sang has worked at prestigious institutions, including the H. Lee Moffitt Cancer Center and Research Institute and the University of South Florida. His work has been instrumental in advancing the understanding of cancer biology and developing new therapeutic strategies.
Collaborations
Peng Sang has collaborated with notable colleagues, including Haitao Ji and Min Zhang. Their combined efforts have contributed to the advancement of research in the field of cancer treatment.
Conclusion
Peng Sang's innovative work and patent contributions have the potential to significantly impact cancer therapy. His research on protein-protein interactions offers promising avenues for developing effective treatments for cancer patients.