Penelope M Drake is a prominent inventor based in Castro Valley, CA (US). She has made significant contributions to the field of biotechnology, particularly in the development of antibody conjugates. With a total of 10 patents to her name, her work has advanced the understanding and application of immunoglobulin technology.

Latest Patents

Drake's latest patents include groundbreaking innovations such as "Antibody conjugates and methods of making and using the same." This patent discloses antibodies that incorporate a sulfatase motif-containing tag in the constant region of an immunoglobulin heavy chain polypeptide. The sulfatase motif can be converted by a formylglycine-generating enzyme to produce a formylglycine-modified Ig heavy chain polypeptide. This modification allows for the covalent and site-specific binding of the antibody to a moiety of interest, resulting in a novel antibody conjugate. Another significant patent is "Camptothecine antibody-drug conjugates and methods of use thereof," which provides structures for antibody-drug conjugates that include a camptothecine or its derivatives linked to a polypeptide through a linker. This patent encompasses methods for the production and application of these conjugates.

Career Highlights

Throughout her career, Penelope has worked with notable companies such as R.P. Scherer Technologies, Inc. and Redwood Bioscience, Inc. Her experience in these organizations has contributed to her expertise in the field of antibody technology and drug development.

Collaborations

Drake has collaborated with esteemed colleagues, including David Rabuka and Robyn M Barfield. These partnerships have fostered innovation and have been instrumental in her research endeavors.

Conclusion

Penelope M Drake is a distinguished inventor whose work in antibody conjugates has made a lasting impact on biotechnology. Her patents reflect her commitment to advancing medical science and improving therapeutic options.

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