The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2023
Filed:
Jan. 13, 2022
Applicant:
R.p. Scherer Technologies, Llc, Carson City, NV (US);
Inventors:
Stepan Chuprakov, Walnut Creek, CA (US);
Ayodele O. Ogunkoya, Berkeley, CA (US);
Penelope M. Drake, Castro Valley, CA (US);
Assignee:
R.P. Scherer Technologies, LLC, Carson City, NV (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/14 (2006.01); C07D 491/22 (2006.01); A61K 47/64 (2017.01); A61K 47/54 (2017.01); C07K 5/062 (2006.01);
U.S. Cl.
CPC ...
A61K 47/545 (2017.08); A61K 47/64 (2017.08); C07D 471/14 (2013.01); C07D 491/22 (2013.01); C07K 5/06026 (2013.01);
Abstract
The present disclosure provides antibody-drug conjugate (ADC) structures, which include a camptothecine or a camptothecine derivative linked to a polypeptide (e.g., an antibody) through a linker. The disclosure also encompasses compounds and methods for production of such conjugates, as well as methods of using the conjugates.