Company Filing History:
Years Active: 1998
Title: Penelope J Toothman: Innovator in Oligonucleotide Ligands
Introduction
Penelope J Toothman is a notable inventor based in the United States. She has made significant contributions to the field of biotechnology, particularly in the development of high-affinity oligonucleotide ligands to growth factors. Her work has implications for various therapeutic applications.
Latest Patents
Penelope J Toothman holds a patent titled "High Affinity Oligonucleotide Ligands To Growth Factors." This invention describes methods for identifying and preparing high-affinity nucleic acid ligands to TGF.beta., PDGF, and hKGF. The patent includes specific RNA and ssDNA ligands to TGF.beta.1 and PDGF identified by the SELEX method. Additionally, it features RNA ligands that inhibit the interaction of TGF.beta.1 and hKGF with their receptors, as well as DNA ligands that inhibit the interaction of PDGF with its receptor. Despite her innovative work, she currently has 2 patents.
Career Highlights
Penelope is associated with Gilead Sciences, Inc., where she continues to advance her research in biotechnology. Her expertise in oligonucleotide ligands has positioned her as a valuable asset in her field.
Collaborations
Throughout her career, Penelope has collaborated with esteemed colleagues, including Larry M Gold and Nebojsa Janjic. These partnerships have further enriched her research and contributions to the scientific community.
Conclusion
Penelope J Toothman is a pioneering inventor whose work in oligonucleotide ligands has the potential to impact therapeutic strategies significantly. Her dedication to innovation in biotechnology continues to inspire advancements in the field.