Peikun Tian

Title: Peikun Tian: Innovator in Tumor Gene Therapy

Introduction

Peikun Tian is a prominent inventor based in Shanghai, China. He has made significant contributions to the field of gene therapy, particularly in targeting tumor cells. His innovative work has the potential to revolutionize cancer treatment.

Latest Patents

Peikun Tian holds a patent for a "Receptor-mediated gene transfer system for targeting tumor gene therapy." This invention relates to a gene transfer system that binds to a growth factor receptor. It comprises a 4-element complex gene transfer system consisting of ligand oligopeptide, polycationic polypeptide, endosome release oligopeptide, and exogenous DNA. Alternatively, it can consist of a 3-element complex made up of ligand oligopeptide, polycationic polypeptide, and exogenous DNA. The invention exemplifies E5, GE7, GV1, and GV2 systems, which can be targeted for the introduction of exogenous genes into malignant tumor cells or tumor vascular endotheliocytes. These systems have demonstrated the ability to significantly inhibit the growth of tumor cells in animal models when using p15, p16, or p21 as exogenous genes. This system represents a novel approach in tumor gene therapy.

Career Highlights

Peikun Tian is affiliated with the Shanghai Cancer Institute, where he continues to advance his research in gene therapy. His work is characterized by a commitment to developing effective treatments for cancer patients.

Collaborations

Peikun Tian collaborates with Jianren Gu, a fellow researcher, to further enhance the impact of their work in the field of gene therapy.

Conclusion

Peikun Tian's innovative contributions to tumor gene therapy exemplify the potential of targeted gene transfer systems in cancer treatment. His work continues to inspire advancements in medical research and therapy.