Pei Fan

Title: Innovations in Anti-PACAP Antibodies by Pei Fan

Introduction

Pei Fan, based in Bothell, WA, is an accomplished inventor with an impressive portfolio of 30 patents. His work primarily focuses on the development of therapeutics targeting PACAP (Pituitary Adenylate Cyclase-Activating Peptide), a neuropeptide implicated in various physiological and pathophysiological processes.

Latest Patents

Among his latest innovations are patents related to "Methods of treatment with anti-PACAP antibodies." This invention describes antagonistic antibodies and their binding fragments, specifically designed to target PACAP. These antibodies serve to inhibit or neutralize biological effects associated with PACAP, such as vasodilation. The invention includes specific polypeptide sequences and outlines their potential applications in diagnosing and treating disorders linked to PACAP, including headaches and migraines.

Another significant patent by Pei Fan is titled "Anti-PACAP antibodies and uses thereof." This work further elaborates on the antagonistic properties of these antibodies, enhancing the understanding of PACAP-related activities. The focus is on utilizing these antibodies for therapeutic benefits in conditions where PACAP antagonism is advantageous.

Career Highlights

Pei Fan has made significant contributions while working for renowned companies, including H. Lundbeck A/S and Alderbio Holdings LLC. His innovative research and development efforts have led to advancements in therapeutic interventions aimed at improving patient outcomes in neurology.

Collaborations

Throughout his career, Pei Fan has collaborated with distinguished colleagues such as Benjamin H. Dutzar and John A. Latham. These partnerships have fostered a creative environment that promotes breakthrough discoveries in the field of biomedical research.

Conclusion

Pei Fan stands out as a prominent inventor in the realm of therapeutic antibodies targeting PACAP. His research not only expands the understanding of neuropeptides but also paves the way for innovative treatment options for patients suffering from conditions such as migraines. With a substantial number of patents to his name, Pei Fan continues to play a crucial role in advancing medical science and improving health care solutions.