Company Filing History:
Years Active: 2011-2015
Title: Payam Mahboubi: Innovator in Biomolecular Detection
Introduction
Payam Mahboubi is a distinguished inventor based in San Diego, CA, known for his contributions to the field of biomolecular detection. With a total of 4 patents, Mahboubi has made significant advancements in methods for detecting and quantifying biomolecules, particularly in the context of prenatal gender determination.
Latest Patents
One of Mahboubi's latest patents focuses on the detection and quantification of biomolecules using mass spectrometry. This invention outlines a method for detecting target nucleic acids through the use of detector oligonucleotides that are detectable by mass spectrometry. The method leverages the 5' to 3' nuclease activity of a nucleic acid polymerase to cleave annealed oligonucleotide probes from hybridized duplexes, releasing labels for detection. This innovative process can be easily integrated into polymerase chain reaction (PCR) amplification assays and includes embodiments for quantitative analysis of target nucleic acids.
Another notable patent by Mahboubi involves nucleic acid-based tests for prenatal gender determination. This invention provides compositions, processes, and kits for the noninvasive and early determination of fetal sex from extracellular nucleic acid samples obtained from pregnant females. The technology is particularly useful for detecting low genomic copy numbers of male fetal nucleic acid amidst a high copy number background of female nucleic acid, thereby allowing for accurate determination of fetal sex and quantification of fetal nucleic acid in samples.
Career Highlights
Throughout his career, Mahboubi has worked with prominent companies in the biotechnology sector, including Sequenom, Inc. and Agena Bioscience, Inc. His work has significantly impacted the development of innovative diagnostic tools and methodologies in the field of molecular biology.
Collaborations
Mahboubi has collaborated with notable professionals in his field, including Paul Andrew Oeth and Dirk Johannes Van Den Boom. These collaborations have further enhanced his research and development efforts, contributing to the advancement of biomolecular detection technologies.
Conclusion
Payam Mahboubi's innovative work in biomolecular detection has led to significant advancements in the field, particularly in prenatal diagnostics. His contributions continue to influence the development of noninvasive testing methods, showcasing the importance of innovation in healthcare.