Company Filing History:
Years Active: 2013-2014
Title: Pavel A Pevzner: Innovator in Peptide Identification and Protein Sequencing
Introduction
Pavel A Pevzner is a prominent inventor based in La Jolla, California. He has made significant contributions to the fields of peptide identification and protein sequencing. With a total of 2 patents, his work has advanced the methodologies used in mass spectrometry.
Latest Patents
Pevzner's latest patents include a "Method for identifying peptides using tandem mass spectra by dynamically determining the number of peptide reconstructions required." This innovative method utilizes a scoring function to match the spectrum of a peptide with candidate peptides in a database. The scoring function evaluates the number of fragment peaks that correspond between the spectrum and the candidate peptide. By computing a generating function of the spectrum, the method determines the number of candidate peptides for each match score, ultimately calculating the probability of a peptide having a specific match score.
Another notable patent is the "Method for identification and sequencing of proteins." In this process, protein samples are transformed into a mixture of modified and unmodified peptides, which are then analyzed using mass spectrometry. This method significantly reduces noise in individual MS/MS spectra by correlating the spectra of peptide pairs. It allows for the de novo reconstruction of protein sequences and identification of peptides and modifications through rapid pattern matching, streamlining the analysis process.
Career Highlights
Pavel A Pevzner is affiliated with the University of California, where he continues to contribute to research and innovation in his field. His work has garnered attention for its practical applications in biotechnology and medicine.
Collaborations
Pevzner has collaborated with notable colleagues, including Sangtae Kim and Nitin Gupta, further enhancing the impact of his research through teamwork and shared expertise.
Conclusion
Pavel A Pevzner's contributions to peptide identification and protein sequencing have established him as a key figure in the field. His innovative patents reflect a commitment to advancing scientific knowledge and practical applications in mass spectrometry.