Company Filing History:
Years Active: 1992-2000
Title: Paulus J Krimpenfort: Innovator in Transgenic Research
Introduction
Paulus J Krimpenfort is a notable inventor based in Amsterdam, Netherlands. He has made significant contributions to the field of transgenic research, particularly in the development of non-human animals with specific genetic modifications. With a total of four patents to his name, Krimpenfort's work has implications for both scientific research and potential therapeutic applications.
Latest Patents
Krimpenfort's latest patents include innovative methods for creating transgenic mice that exhibit a phenotype characterized by the substantial depletion of a mature lymphocytic cell type. This phenotype is conferred by a transgene contained in the precursor stem cell of the lymphocytic cell type that is depleted. The transgene comprises a DNA sequence encoding a lymphatic polypeptide variant that inhibits the maturation of the lymphocytic cell type. These advancements represent a significant step forward in understanding immune system functions and developing new treatments.
Career Highlights
Throughout his career, Krimpenfort has been associated with Genpharm International, Inc., where he has collaborated with other researchers to push the boundaries of genetic engineering. His work has not only advanced scientific knowledge but has also paved the way for potential medical breakthroughs.
Collaborations
One of his notable collaborators is Antonius J Berns, with whom he has worked closely on various projects related to transgenic animals. Their combined expertise has led to significant advancements in the field.
Conclusion
Paulus J Krimpenfort's contributions to transgenic research highlight the importance of innovation in the life sciences. His patents and collaborations continue to influence the scientific community and open new avenues for research and development.