Company Filing History:
Years Active: 2016-2017
Title: Pauline McGann: Innovator in Biological Material Selection
Introduction
Pauline McGann is a notable inventor based in Miami Beach, FL (US). She has made significant contributions to the field of biological material selection, holding 2 patents that showcase her innovative approaches.
Latest Patents
Her latest patents focus on methods and reagents for improved selection of biological materials. These patents describe methods, apparatus, and compositions for separating a desired or undesired population or subpopulation from a biological sample. The selection procedure utilizes ferromagnetic, dense particles in a preferred size range from about 0.8 to about 1.2 microns. Specific binding agents are attached to these particles, allowing them to recognize and bind to specific molecules on the targeted population or subpopulation. The particles are mixed with the sample to promote their movement relative to the sample, enhancing the binding to the targeted population while minimizing non-specific binding to non-targeted populations. Due to the large particle density, the bound population can be separated from the fluid sample by gravity. Alternatively, the sample, including the bound targeted population, can be placed in a magnetic field, allowing the particles to separate from the sample by evenly distributing over the vessel wall, thus limiting non-specific trapping of the non-targeted population.
Career Highlights
Throughout her career, Pauline has worked with reputable companies such as Janssen Diagnostics, LLC and Russell Biotech, Inc. Her work has significantly impacted the field of diagnostics and biotechnology.
Collaborations
Some of her notable coworkers include Thomas R. Russell and Mike Musick, who have collaborated with her on various projects.
Conclusion
Pauline McGann's innovative work in the selection of biological materials has established her as a prominent figure in her field. Her patents reflect her commitment to advancing technology in biological research and diagnostics.