Company Filing History:
2 out of 1,743 
2 out of 99 
2 out of 10 
Years Active: 2020-2023
Title: Innovations in Antibody Therapy: The Contributions of Paulette Legendre
Introduction
Paulette Legendre is a notable inventor based in Le Kremlin-Bicetre, France, recognized for her pioneering work in the field of monoclonal antibodies. With a total of two patents to her name, Legendre has contributed significantly to medical advancements, particularly in the prevention and treatment of bleeding episodes.
Latest Patents
Legendre's latest inventions focus on isolated monoclonal antibodies that specifically target the D4 domain of von Willebrand factor (VWF). These antibodies compete with ADAMTS13 for binding to the VWF D4 domain and partially inhibit its degradation. The detailed specification of her invention reveals that the heavy chain variable domain comprises sequences identified as SEQ ID NO: 3, 4, and 5 for H-CDR1, H-CDR2, and H-CDR3, respectively. The light chain variable domain features sequences selected from SEQ ID NO: 7, 8, and 9 for L-CDR1, L-CDR2, and L-CDR3. The applications of these antibodies are particularly significant for patients at risk of bleeding episodes, such as those with aortic stenosis or utilizing ventricular assist devices (VAD).
Career Highlights
Throughout her career, Paulette Legendre has collaborated with prestigious institutions such as the Institut National de la Santé et de la Recherche Médicale and Université Paris-Sud. Her work has remained at the forefront of antibody research, contributing to innovative solutions in the medical field.
Collaborations
Legendre has worked alongside noteworthy colleagues, including Petrus Lenting and Cécile Denis. Their collaborative efforts have amplified the impact of her research, further advancing the understanding and therapeutic potential of monoclonal antibodies.
Conclusion
Paulette Legendre stands out as an influential inventor in the field of biotechnology. Her targeted innovations in antibody therapy illustrate her commitment to improving patient outcomes and advancing scientific knowledge. Through her patents and collaborative efforts, Legendre continues to make significant contributions to the medical community.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.