This inventor holds 2 USPTO granted patents. Top assignee: Cetus Corporation. Active years: 1989-1992.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Richmond, CA (US) (1989)
- Belmont, CA (US) (1992)
Company Filing History:
Years Active: 1989-1992
Title: **Paula J. Shadle: Innovator in Bioconjugate Technologies**
Introduction
Paula J. Shadle is a notable inventor based in Belmont, California. With a focus on bioconjugate methodologies, she has made significant contributions to the field, securing two patents that showcase her innovative prowess. Her work primarily revolves around enhancing the efficacy of biologically active proteins.
Latest Patents
One of Paula's latest patents, titled "Conjugation of polymer to colony stimulating factor-1," demonstrates her expertise in the manipulation of protein structures. This invention involves the selective conjugation of a biologically active CSF-1 protein to various water-soluble polymers such as polyethylene glycol or polypropylene glycol. The resulting conjugated CSF-1 maintains biological activity while exhibiting an increased circulating half-life in mammals compared to its unconjugated form. This innovative approach has promising applications in stimulating immune responses and enhancing cellular proliferation.
Career Highlights
Paula J. Shadle is currently associated with Cetus Corporation, where she continues to drive research in bioconjugate technologies. Her innovative spirit and scientific acumen have positioned her as a leader in her field, contributing to the development of products that could potentially transform therapeutic practices.
Collaborations
Throughout her career, Paula has collaborated with esteemed colleagues such as Kirston E. Koths and Margaret Moreland. These partnerships have allowed her to merge different expertise areas, ultimately enriching her research and broadening the impact of her inventions.
Conclusion
Paula J. Shadle stands out as an impactful inventor in the realm of bioconjugate technologies. With her innovative patents and collaborations within Cetus Corporation, she continues to pave the way for advancements in immunotherapy and protein engineering. Her work not only highlights her individual talents but also the collective effort necessary to drive innovation in the scientific community.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile