Paula Ann Borden

Title: Innovations by Paula Ann Borden

Introduction

Paula Ann Borden is a notable inventor based in Palo Alto, CA (US). She has made significant contributions to the field of biotechnology, particularly in the area of gene expression and modulation.

Latest Patents

Paula Ann Borden holds 2 patents. Her latest patents include methods for measuring stromelysin-1 promoter activity. This invention relates to a human stromelysin-1 (HSL-1) promoter and its uses. Specifically, it provides a purified DNA containing a functional HSL-1 promoter region that corresponds in structure to the native genomic form of this promoter. The invention also includes an expression vector containing a portion of the purified promoter DNA operatively linked to a heterologous DNA sequence encoding a detectable gene product. Additionally, it involves a host cell transformed with this factor, a pharmacologic screening assay for stromelysin-1 promoter modulating activity, and a method of modulating TNF α level and matrix metalloproteinase activities in inflamed tissues of a mammal.

Career Highlights

Paula Ann Borden has had a distinguished career, working at Syntex (U.S.A.) Inc. Her work has focused on innovative solutions in the biotechnology sector, contributing to advancements in medical research and therapeutic applications.

Collaborations

One of her notable collaborators is Renu Anand Heller, who has worked alongside her in various projects.

Conclusion

Paula Ann Borden's contributions to biotechnology through her patents and collaborations highlight her role as an influential inventor in her field. Her work continues to impact medical research and therapeutic development.