Paul Wooley

Title: Paul Wooley: Innovator in Drug Delivery and Bone Grafting Technologies

Introduction

Paul Wooley is a notable inventor based in Wichita, KS (US), recognized for his contributions to the fields of drug delivery systems and synthetic bone grafts. With a total of 3 patents, Wooley has made significant strides in developing innovative solutions for medical applications.

Latest Patents

One of Wooley's latest patents is a composite magnetic nanoparticle drug delivery system. This system provides targeted controlled release of chemotherapies for cancerous tumors and inflammatory diseases. The magnetic nanoparticle includes a biocompatible and biodegradable polymer, a magnetic nanoparticle, the biological targeting agent human serum albumin, and a therapeutic pharmaceutical composition. The composite nanoparticles are prepared using oil-in-oil emulsion/solvent evaporation and high shear mixing. An externally applied magnetic field draws the magnetic nanoparticles to affected areas, while the biological targeting agent facilitates their entry into the affected tissues. The polymer degradation allows for controlled time release delivery of the pharmaceutical agent.

Another significant patent involves synthetic bone grafts constructed from carbon foam materials. This invention presents a porous, self-sustaining body that serves as a scaffold for bone grafting. The scaffold comprises a carbonaceous matrix with a continuous phase that defines a plurality of open spaces throughout. The internal and external surfaces of the matrix are coated with a layer or film selected from osteogenic materials, therapeutic agents, and combinations thereof. The porous body is made from organic materials and is substantially free of metals. Methods for making and using this porous self-sustaining body are also provided, along with kits to facilitate the process.

Career Highlights

Throughout his career, Paul Wooley has worked with various organizations, including Cibor, Inc. and Wichita State University. His experience in these institutions has contributed to his innovative research and development efforts.

Collaborations

Some of Wooley's notable coworkers include Ramazan Asmatulu and Heath Edward Misak. Their collaborative efforts have further advanced the research and applications of his inventions.

Conclusion

Paul Wooley's innovative work in drug delivery systems and synthetic bone grafts showcases his commitment to advancing medical technology. His patents reflect a deep understanding of both materials science and biomedical engineering, making significant contributions to healthcare solutions.