This inventor holds 1 USPTO granted patent. Top assignee: Triad National Security, LLC. Active years: 2021.
Company Filing History:
Years Active: 2021
Title: Paul William Peterson: Innovator in Peptoid Cyclization
Introduction
Paul William Peterson is a notable inventor based in Los Alamos, NM (US). He has made significant contributions to the field of chemistry, particularly in the area of peptoid cyclization. His innovative work has led to advancements that could impact drug delivery systems.
Latest Patents
One of Peterson's key patents is titled "Controlled cyclization of peptoids to form chiral diketopiperazines." This patent outlines improved methods for the controlled cyclization of peptoid dimers to create N,N'-2,5-diketopiperazines (N,N'-2,5-DKPs) with significant selectivity. The methods described leverage a combination of factors, including the slow exchange of amide rotamers and steric repulsion, to enhance selectivity. By adjusting reaction conditions, the formation of specific N,N'-2,5-DKPs can be manipulated. This cyclization process is versatile, functioning effectively in the presence of various protection groups and functionalities. The techniques provided in this patent facilitate the synthesis of N,N'-2,5-DKPs that can be easily docked with drug candidates, potentially improving their ability to cross the blood-brain barrier.
Career Highlights
Paul William Peterson is currently associated with Triad National Security, LLC, where he continues to explore innovative solutions in his field. His work has garnered attention for its potential applications in pharmaceuticals and drug development.
Collaborations
Throughout his career, Peterson has collaborated with esteemed colleagues, including Jurgen G Schmidt and Robert F Williams. These partnerships have contributed to the advancement of his research and the successful development of his patented methods.
Conclusion
Paul William Peterson's contributions to the field of chemistry, particularly through his patent on peptoid cyclization, highlight his role as an innovator. His work not only advances scientific understanding but also holds promise for future applications in drug delivery systems.