Company Filing History:

12 out of 4,770

Merck + Co., Inc.

where one patent can have more than one assignee

Years Active: 1978-1998

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12 patents (USPTO):Sort by Forward Citations

Abstract keywords

1. 5777105 - Process for the preparation of imidazolyl macrolide immunosuppressants (1998-07-07),

2. 5760249 - Synthesis of hydroxysulfone and related compounds (1998-06-02),

3. 5693805 - Process to derivatives of piperizinylcamphorsulfonyl oxytocin antagonists (1997-12-02),

4. 5688968 - Enantioselective synthesis of (1997-11-18),

5. 5574176 - Synthesis of an intermediate for the preparation of (1996-11-12),

6. 5157129 - Enantiospecific synthesis of (1992-10-20),

7. 5011942 - Process for racemizing an enantiomer of (1991-04-30),

8. 4992541 - Process for the preparation of 1,1-dioxo-7-substituted cephems (1991-02-12),

9. 4968814 - (S)-Alkyl 3-(thien-2-ylthio)butyrate and analogs and synthesis thereof (1990-11-06),

10. 4220762 - Process for the preparation of cephamycin antibiotics (1980-09-02),

11. 4218563 - Process for the preparation of cephamycin antibiotics (1980-08-19),

12. 4093657 - Process for preparing monomer of bile acid sequestrant polymer (1978-06-06),

Title: The Innovative Journey of Paul Sohar

Introduction

Paul Sohar is an accomplished inventor based in Warren, NJ, with an impressive portfolio of 12 patents. His contributions to the field of immunosuppressants and pharmaceuticals highlight his innovative spirit and commitment to improving medical therapies.

Latest Patents

Among his notable recent patents is a process for the preparation of imidazolyl macrolide immunosuppressants. This invention details the reaction of a tricyclo-macrolide with an imidazolmethyl trichloroacetimidate in the presence of acid, leading to the creation of crystalline salts of imidazolmethyloxy-substituted tricyclo-macrolide. These compounds are significant in the formulation of immunosuppressive drugs.

Another crucial patent of Sohar's is the synthesis of hydroxysulfone and related compounds, which pertains to an improved method for producing hydroxysulfone. This compound serves as a fundamental intermediate in the creation of carbonic anhydrase inhibitors, such as dorzolamide, which are vital in treating conditions like elevated intraocular pressure and glaucoma.

Career Highlights

Throughout his career, Paul Sohar has made an impact by working with prominent companies in the pharmaceutical industry, including Merck & Company, Inc. and Zeneca Limited. His tenure in these organizations has allowed him to develop groundbreaking solutions that address various medical challenges.

Collaborations

Sohar has collaborated with esteemed colleagues, including David J. Mathre and Thomas J. Blacklock. These partnerships have fostered discussions and explorations that further enriched his inventions and innovations in the pharmaceutical field.

Conclusion

Paul Sohar's contributions to science are evident through his numerous patents and innovative processes. His work not only advances the field of immunosuppressants but also significantly impacts treatments for various medical conditions. As he continues to pursue new avenues of invention, his legacy as a dedicated inventor is firmly established.

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