Paul P Beroza

Title: **Paul P. Beroza: Innovator in Carboxylesterase Inhibitors**

Introduction

Paul P. Beroza, based in Redwood City, California, is an accomplished inventor known for his contributions to the field of pharmaceuticals and pesticide formulations. With a focus on developing carboxylesterase inhibitors, Beroza has patented innovative compounds that demonstrate significant potential in both medical and agricultural applications.

Latest Patents

Beroza holds a patent titled "Amide, aryl sulfonamide, aryl urea, and α,β-diketone derived carboxylesterase inhibitors, and their methods of use." This patent encompasses amides, aryl sulphonamides, aryl ureas, and α,β-diketone derivatives that serve as carboxylesterase inhibitors. The compounds disclosed are significant for their selective inhibition of human intestinal carboxylesterases and insect carboxylesterases. Additionally, the patent indicates potential applications of these compounds in pharmaceutical compositions and insecticide formulations, particularly for treating or reducing toxic effects associated with drug overdoses and enhancing the efficacy of pesticides.

Career Highlights

Paul P. Beroza is affiliated with St. Jude Children's Research Hospital, where his research focuses on using innovative therapeutic strategies to address critical health challenges. His work in developing carboxylesterase inhibitors is crucial in addressing toxicity issues in drug administration and improving pesticide effectiveness, marking him as a key contributor in his field.

Collaborations

Throughout his career, Beroza has collaborated with fellow researchers, including Philip Michael Potter and Janice Louise Hyatt. These partnerships underscore the collaborative efforts often necessary in scientific research, leading to advancements in understanding and application of carboxylesterase inhibitors.

Conclusion

Paul P. Beroza's innovative patent on carboxylesterase inhibitors reflects his commitment to advancing pharmaceutical and agricultural sciences. His work at St. Jude Children's Research Hospital, along with his collaborations, positions him as a notable inventor in the realm of drug safety and pest management solutions. As the field evolves, Beroza's contributions will likely have lasting impacts on both healthcare and agricultural practices.