Paul Nathan Patrone

Title: Paul Nathan Patrone: Innovator in Flow Cytometry

Introduction

Paul Nathan Patrone is a distinguished inventor based in Washington Grove, MD (US). He has made significant contributions to the field of flow cytometry, holding a total of 3 patents. His work focuses on developing advanced devices that enhance the measurement and analysis of particles in fluid samples.

Latest Patents

One of Patrone's latest inventions is the serial flow cytometer. This device is designed to measure single particles in flow multiple times along a microchannel. It incorporates integrated waveguides that facilitate the transmission of optical signals, such as excitation, emission, and scattered light, to and from measurement regions. This innovation allows for multiple measurements of particles, including microspheres and cells, traveling through a microfluidic channel. The technology achieves lower uncertainties and can effectively discriminate complex samples while accounting for various sources of uncertainty related to the shape, deformability, stability, or activity of objects in a liquid sample.

Another notable patent is the multiplexed amplitude modulation photometer. This device includes a microchannel and features multiple input light paths that receive modulated light at different frequencies. It communicates this light to optical regions that analyze different analytes, producing output light that is then detected through dedicated detection light paths. This technology enhances the ability to perform multiplexed amplitude modulation photometry, allowing for more efficient and accurate measurements.

Career Highlights

Paul Nathan Patrone is currently employed by the Government of the United States of America, as represented by the Secretary of Commerce. His work in this capacity has allowed him to contribute to significant advancements in scientific research and technology.

Collaborations

Throughout his career, Patrone has collaborated with notable colleagues, including Gregory Alan Cooksey and Anthony Jose Kearsley. These partnerships have fostered innovation and have been instrumental in the development of his patented technologies.

Conclusion

Paul Nathan Patrone is a prominent inventor whose work in flow cytometry has led to groundbreaking advancements in the measurement of particles in fluid samples. His contributions continue to impact the field significantly, showcasing the importance of innovation in scientific research.