Company Filing History:
2 out of 3 
1 out of 1 
1 out of 29 Years Active: 1998-2001
Title: Paul M Walker: Innovator in Blood Analyte Measurement
Introduction
Paul M Walker is a notable inventor based in Toronto, Canada, recognized for his contributions to the field of medical diagnostics. He holds four patents that focus on innovative methods for measuring analytes in whole blood, which are crucial for diagnosing various medical conditions.
Latest Patents
Walker’s latest patents include groundbreaking methods for the measurement and quantitation of analytes in blood samples. One of his inventions relates to a method for measuring the level of a preselected analyte in a sample of blood from a human or animal patient. This method involves incubating the test sample with an antibody specific to the analyte, forming an immunocomplex that interacts with white blood cell fractions, resulting in the production of oxidants. These oxidants are detected using chemiluminescent reagents. The assay also includes a measurement of oxidant production from a maximal stimulatory dose of immunocomplexes, providing a ratio to indicate the analyte level in the sample. This method can be used to determine levels of various analytes, including endotoxin and inflammatory mediators, which are essential for selecting appropriate therapeutic courses.
Another patent focuses on quantitating the level of a preselected analyte in blood samples. Similar to the previous method, it involves incubating the test sample with a specific antibody to form immunocomplexes. The oxidant response can be enhanced by including agents such as opsonized zymosan. This quantitative method is vital for measuring analytes related to sepsis and other medical conditions.
Career Highlights
Throughout his career, Paul M Walker has worked with several companies, including Sepsis Limited and Critichem Medical Products Limited. His work has significantly impacted the field of medical diagnostics, particularly in the area of sepsis detection and treatment.
Collaborations
Walker has collaborated with notable individuals in his field, including Alexander D Romaschin and Alex D Romaschin. These collaborations have contributed to the advancement of his research and innovations.
Conclusion
Paul M Walker is a distinguished inventor whose work in blood analyte measurement has the potential to improve diagnostic methods and patient care. His innovative patents reflect his commitment to advancing medical technology and enhancing the understanding of various health conditions.