Location History:
- Ouernavaca, MX (1996)
- Colonia Rancho Cortez Cuernavaca, MX (1997)
- Privada Cerritos, MX (1998)
- Hamden, CT (US) (2000 - 2003)
- Wallingford, CT (US) (2001 - 2004)
- Cuernavaca, MX (1992 - 2009)
- San Antonio, TX (US) (2021)
Company Filing History:
16 out of 1,325 
5 out of 29 
4 out of 2,487 
Years Active: 1992-2021
Title: Innovations of Paul M Lizardi: Pioneering Nucleic Acid Detection Methods
Introduction
Paul M Lizardi, an accomplished inventor based in Wallingford, CT, has made significant contributions to the field of molecular biology with an impressive portfolio of 31 patents. His inventions focus on enhancing nucleic acid detection methods, which play a vital role in various biological applications.
Latest Patents
Among Lizardi's latest patents are two groundbreaking innovations. The first, "Rolling Circle Replication Reporter Systems," details a composition and method for amplifying nucleic acid sequences that are crucial for detecting specific molecules in a sample with high accuracy and sensitivity. This method is engineered to minimize background noise while achieving high levels of signal specificity through a DNA ligation operation, followed by rolling circle replication. The result is a precise quantitative measurement of target nucleic acids, with advantages including isothermal DNA replication and the ability to perform multiplex assays.
The second patent, "Ultra-Sensitive Detection Systems Using Alterable Peptide Tags," presents innovative methods for the sensitive detection of one or multiple analytes. This invention utilizes unique reporter signals that can be distinctively altered, enhancing the capability to discern between various analytes. The flexibility in using common properties to differentiate reporter signal/analyte conjugates provides a robust framework for complex biological analyses.
Career Highlights
Lizardi has a rich background working with prestigious institutions such as Yale University and The Public Health Research Institute of the City of New York, Inc. His association with these organizations underscores his commitment to advancing research in molecular detection technologies.
Collaborations
Throughout his career, Lizardi has collaborated with notable figures in the scientific community, including Fred Russell Kramer and Sanjay Tyagi. These partnerships have contributed to the innovation and refinement of his discoveries, further enhancing their impact on the field.
Conclusion
In conclusion, Paul M Lizardi's extensive work and inventive spirit continue to push the boundaries of nucleic acid detection methodologies. His patents reflect a promising future for research and practical applications in molecular biology, solidifying his legacy as a key figure in the field of scientific innovation.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.