Paul L Bergstein

Title: Paul L Bergstein: Innovator in Radiopharmaceuticals

Introduction

Paul L Bergstein is a notable inventor based in Norwood, MA (US). He has made significant contributions to the field of radiopharmaceuticals, holding a total of 3 patents. His work focuses on the development of innovative compounds that enhance medical imaging techniques.

Latest Patents

Bergstein's latest patents include the invention of ester-substituted diaminedithiols and radiolabeled complexes thereof. These radiopharmaceuticals consist of a lipophilic, charge-neutral radionuclide complex of a diaminedithiol ligand. The ligand features 1-4 ester groups of the formula --A--COOR, where A is a straight or branched chain alkylene of 0-10 carbon atoms, and R is an alkyl group of 1-10 carbon atoms. These compounds are particularly useful in radioimaging brain perfusion in primates. Additionally, the patents provide ester-substituted diaminedithiols in sterile, pharmaceutically acceptable form, along with kits containing the diaminedithiols and sterile, non-pyrogenic reducing agents for reducing preselected radionuclides. Technetium-99m is identified as a preferred radionuclide in these applications.

Career Highlights

Throughout his career, Paul L Bergstein has worked with prominent companies in the pharmaceutical industry, including the DuPont Merck Pharmaceutical Company and E.I. du Pont de Nemours and Company. His experience in these organizations has contributed to his expertise in the development of innovative medical solutions.

Collaborations

Bergstein has collaborated with notable colleagues such as Edward H Cheesman and Alan D Watson. These partnerships have likely enriched his research and development efforts in the field of radiopharmaceuticals.

Conclusion

Paul L Bergstein's contributions to the field of radiopharmaceuticals demonstrate his commitment to advancing medical imaging technologies. His innovative patents and collaborations highlight his role as a significant inventor in this specialized area.