Company Filing History:
Years Active: 2005-2013
Title: Paul K Goldsmith: Innovator in Tumor Diagnosis and Treatment
Introduction
Paul K Goldsmith is a notable inventor based in Rockville, MD (US). He has made significant contributions to the field of medical research, particularly in the diagnosis and treatment of tumors. With a total of 3 patents to his name, Goldsmith's work focuses on innovative therapies that target specific cancer mechanisms.
Latest Patents
Goldsmith's latest patents include compositions and methods for the diagnosis and treatment of tumors. His research is based on the cooperation of osteopontin (OPN) and matrix metalloproteinase-9 (MMP-9) in promoting the metastatic phenotype. These patents disclose therapies and diagnostic assays for treating tumors that overexpress OPN, such as hepatocellular carcinoma (HCC). One example of his methods involves administering an agent that reduces cellular invasion resulting from the interaction between a fragment of OPN (OPN-5kD) generated by MMP-9 cleavage and the CD44 receptor. The agents include fragments of OPN-5kD and antibodies specific for OPN-5kD. Additionally, Goldsmith provides methods for diagnosing or prognosing a tumor by detecting the expression of OPN-5kD peptide or OPN-c mRNA in biological samples.
Career Highlights
Goldsmith is currently affiliated with the National Institutes of Health, a component of the US Department of Health & Human Services. His work at this prestigious institution allows him to collaborate with leading experts in the field and contribute to groundbreaking research.
Collaborations
Some of Goldsmith's notable coworkers include Vivian Takafuji and Xin Wei Wang. Their collaborative efforts enhance the research environment and foster innovation in cancer treatment.
Conclusion
Paul K Goldsmith is a distinguished inventor whose work in tumor diagnosis and treatment has the potential to significantly impact cancer therapy. His innovative approaches and collaborations continue to advance the field of medical research.