Company Filing History:
Years Active: 2023-2025
Title: Innovations by Paul-Joseph Penaflor-Aspuria: A Pioneer in Cytokine Research
Introduction
Paul-Joseph Penaflor-Aspuria is an innovative inventor residing in Redwood City, CA, who has made significant contributions to the field of biomedical research. He is particularly known for his work on interleukin-2 (IL-2) orthologs and their applications in cell signaling. With one patent to his name, his invention has the potential to influence therapeutic approaches in immunology.
Latest Patents
Paul-Joseph Penaflor-Aspuria holds a patent for "IL-2 orthologs and methods of use." This patent refers to human IL-2 orthogonal ligands (IL-2 orthologs) that specifically and selectively bind to the extracellular domain of a modified hCD122 polypeptide. The invention details how the binding process participates in intracellular signaling pathways, leading to biological activities similar to those associated with native hIL-2. The orthologs show reduced binding affinity to wild type hCD122, making them particularly useful for engineered cells expressing the hCD122 orthogonal receptor.
Career Highlights
Currently, Paul-Joseph is associated with Synthekine, Inc., a company that focuses on the development of engineered proteins for therapeutic purposes. His role at Synthekine showcases his commitment to advancing medical science through innovative research and development in the field of cytokines.
Collaborations
Throughout his career, Paul-Joseph Penaflor-Aspuria has collaborated with notable professionals in his field, including Scott Alan McCauley and Martin Oft. These collaborations have contributed to the advancement of research and development in cytokine therapeutics, paving the way for potential breakthroughs in immunological treatments.
Conclusion
Paul-Joseph Penaflor-Aspuria stands out as a significant innovator in the biomedical sector, particularly in immunology. His work on IL-2 orthologs illustrates the potential of engineered biological molecules in advancing therapeutic techniques. As research continues to evolve, the implications of his inventions will likely play a crucial role in the future of medical treatments.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.