Brookline, MA, United States of America

Paul J Tempest


Average Co-Inventor Count = 11.0

ph-index = 1

Forward Citations = 17(Granted Patents)


Company Filing History:


Years Active: 2011

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1 patent (USPTO):

Title: The Innovative Contributions of Paul J. Tempest

Introduction

Paul J. Tempest is a distinguished inventor based in Brookline, MA, known for his innovative work in the field of pharmaceuticals. With a focus on cancer treatment, he has made significant strides in developing new compounds that offer promise in the fight against neoplastic cells.

Latest Patents

Tempest holds one patent titled "Phosphorus Derivatives as Histone Deacetylase Inhibitors". This groundbreaking invention revolves around a novel class of phosphorus derivatives that have shown efficacy in treating cancer. The patented phosphorus compounds not only inhibit histone deacetylase but are also capable of inducing terminal differentiation and arresting the growth and apoptosis of neoplastic cells. Furthermore, the compounds demonstrate potential in addressing TRX-mediated diseases, autoimmune diseases, and neurodegenerative diseases of the central nervous system (CNS). The patent also outlines pharmaceutical compositions containing these derivatives, proposing safe dosing regimens to achieve therapeutic effectiveness in patients.

Career Highlights

Tempest is currently affiliated with Merck Sharp & Dohme Corporation, where he applies his expertise in medicinal chemistry and drug development. His work contributes to the advancement of therapeutic strategies aimed at combatting serious health challenges, particularly cancer and other chronic diseases.

Collaborations

Throughout his career, Tempest has collaborated with esteemed colleagues such as Joshua Close and Jonathan B. Grimm. These partnerships enhance the research environment and foster innovation, leading to more comprehensive solutions in their scientific endeavors.

Conclusion

In conclusion, Paul J. Tempest stands out as a notable inventor in the pharmaceutical industry, contributing valuable inventions that hold promise for improving patient outcomes in cancer treatment and other serious medical conditions. His innovative research and collaborative efforts continue to pave the way for advancements in healthcare.

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