This inventor holds 2 USPTO granted patents and 1 published patent application. Top assignee: Glycomed, Inc.. Active years: 1991-1992.
Company Filing History:
Years Active: 1991-1992
Title: Paul G. James: Innovator in Electrophoretic Techniques
Introduction
Paul G. James is a notable inventor based in Alameda, CA (US). He has made significant contributions to the field of electrophoretic techniques, particularly in the area of saccharide analysis. With a total of 2 patents, his work has advanced the understanding of protein-sugar interactions.
Latest Patents
One of Paul G. James's latest patents focuses on the electro-blotting of electrophoretically resolved fluorescent-labeled saccharides. This innovative method allows for the separation of saccharides into groups or individual components, which can then be tested for their affinity for specific proteins. The process involves conjugating saccharides with charge-generating moieties and fluorescent moieties, such as 4-amino-1-naphthalene sulfonic acid (ANSA). The resulting saccharide conjugates undergo electrophoretic resolution within gels, and the resolved bands are electro-blotted onto charged nylon membranes. This technique provides a stable record of the electrophoretic separation, enabling researchers to determine the binding affinity of proteins to saccharides effectively.
Career Highlights
Paul G. James has been instrumental in developing methods that enhance the detection and analysis of saccharides in various mixtures. His work at Glycomed, Inc. has positioned him as a key figure in the field of biochemistry and molecular biology. His innovative approaches have paved the way for advancements in understanding complex biological interactions.
Collaborations
Throughout his career, Paul has collaborated with esteemed colleagues, including Michael Tiemeyer and Brian K. Brandley. These partnerships have fostered a collaborative environment that encourages innovation and the sharing of ideas.
Conclusion
Paul G. James is a distinguished inventor whose work in electrophoretic techniques has significantly impacted the field of biochemistry. His contributions continue to influence research and development in understanding protein-sugar interactions.