Paul F Sieving

Title: Paul F Sieving: Innovator in Diagnostic Imaging

Introduction

Paul F Sieving is a notable inventor based in San Jose, CA, with a focus on innovations in the field of diagnostic imaging. He holds three patents that showcase his contributions to medical technology and imaging techniques. His work has significantly advanced the understanding and application of polychelants and their metal chelates.

Latest Patents

One of Sieving's latest patents is directed to polychelants and their metal chelates, which are useful in diagnostic imaging. The invention comprises a plurality of macrocyclic chelant moieties, such as DOTA residues, conjugated by thiourea, urea, or glycinamide linkages to a backbone moiety through a donor atom. Another significant patent involves adducts of macrocyclic chelants, which are also useful in diagnostic imaging and radiotherapy. This invention includes polychelants that consist of macrocyclic chelant moieties conjugated to a polyamine backbone molecule, such as polylysine. The process to produce a site-specific polychelate involves several steps, including dispersing a carboxylic macrocyclic chelant in a polar, anhydrous solvent and adding a base to create an amine salt of the chelant.

Career Highlights

Throughout his career, Paul F Sieving has worked with various companies, including Salutar, Inc. His innovative work has led to advancements in the medical field, particularly in the area of diagnostic imaging technologies.

Collaborations

Sieving has collaborated with notable individuals in his field, including Alan D Watson and Steven C Quay. These collaborations have contributed to the development of his patents and the advancement of diagnostic imaging techniques.

Conclusion

Paul F Sieving's contributions to the field of diagnostic imaging through his innovative patents highlight his role as a significant inventor. His work continues to influence advancements in medical technology and imaging applications.