This inventor holds 1 USPTO granted patent. Top assignee: The United States of America as Represented by the Department of Health. Active years: 1998.
Company Filing History:
Years Active: 1998
Title: The Innovative Contributions of Paul F. Morrison
Introduction
Paul F. Morrison is a notable inventor based in Bethesda, MD (US). He has made significant contributions to the field of medical technology, particularly in drug delivery systems. His innovative approach has the potential to enhance treatment options for various medical conditions.
Latest Patents
Morrison holds a patent for a method titled "Convection-enhanced drug delivery." This method involves high-flow microinfusion, which provides convection-enhanced delivery of agents into the brain and other solid tissue structures. The technique requires positioning the tip of an infusion catheter within a tissue structure and supplying an agent through the catheter while maintaining a pressure gradient during infusion. Experimental delivery rates of 0.5 to 15.0 µl/min have been utilized, achieving infusion distances greater than 1 cm from the delivery source. This method can be applied to deliver various drugs, protein toxins, antibodies for treatment or imaging, proteins in enzyme replacement therapy, growth factors for neurodegenerative disorders, and even viruses and gene therapy. The infusion catheter developed for this high-flow microinfusion includes elongated slits adjacent to a tapered portion, which are parallel to the catheter's axis and symmetrically spaced around its circumference.
Career Highlights
Morrison's work is represented by the United States of America as represented by the Department of Health. His innovative contributions have been recognized within the medical community, showcasing his commitment to advancing healthcare technology.
Collaborations
Some of his notable coworkers include Richard Hunt Bobo and Douglas W. Laske. Their collaborative efforts have furthered the development of innovative medical solutions.
Conclusion
Paul F. Morrison's contributions to convection-enhanced drug delivery exemplify the impact of innovation in medical technology. His work continues to pave the way for improved treatment methodologies in healthcare.