Location History:
- San Diego, CA (US) (1989)
- Jolla, CA (US) (1989)
Company Filing History:
Years Active: 1989
Title: Paul F Brust: Innovator in Gene Expression Technologies
Introduction
Paul F Brust is a notable inventor based in San Diego, California. He has made significant contributions to the field of biotechnology, particularly in the area of gene expression in yeast. With a total of 2 patents, Brust's work has advanced the understanding and application of genetic engineering.
Latest Patents
Brust's latest patents include innovative methods and constructs for gene expression. One patent focuses on a regulatory region for heterologous gene expression in yeast. This invention provides novel DNA sequences that respond to the presence of methanol, catabolite non-repressing carbon sources, and carbon source starvation. The patent details processes for producing these DNA sequences and constructs, demonstrating the production of polypeptide products under the control of the regulatory regions. Another patent involves a method for isolating and cloning methanol-inducible genes from Pichia. This method highlights the utility of regulatory regions for methanol-regulated expression of heterologous genes.
Career Highlights
Paul F Brust is currently associated with Phillips Petroleum Company, where he applies his expertise in biotechnology. His work has contributed to advancements in genetic engineering and the production of valuable bioproducts.
Collaborations
Brust has collaborated with notable colleagues, including David W Stroman and Steven B Ellis. These collaborations have further enriched his research and development efforts in the field.
Conclusion
Paul F Brust's innovative work in gene expression technologies has made a significant impact in biotechnology. His patents reflect a commitment to advancing the field and improving methods for genetic engineering.