Paul C A Bulpitt

Title: Paul C A Bulpitt: Innovator in Hyaluronan Derivatives

Introduction

Paul C A Bulpitt is a notable inventor based in Stoneham, MA (US). He has made significant contributions to the field of biochemistry, particularly in the development of hyaluronan derivatives. With a total of 2 patents, his work focuses on innovative drug delivery systems.

Latest Patents

Bulpitt's latest patents include advancements in thiol-modified hyaluronan. The first patent relates to biscarbodiimides, thiourea derivatives, urea derivatives, and cross-linked hyaluronan derivatives that possess at least one intramolecular disulfide bond. This invention also encompasses thiolated hyaluronan derivatives and salts with at least one pendant thiol group or a modified pendant thiol group. An example of a modified pendant thiol group is a sulfhydryl group linked to a small molecule, such as a bioactive agent or a drug. These hyaluronan derivatives are particularly useful as sustained or controlled release drug delivery vehicles. They can reversibly viscosify in vivo or in vitro in response to mild changes in conditions, making them valuable in ophthalmic surgery and tissue engineering.

Career Highlights

Bulpitt is currently associated with Anika Therapeutics, Inc., where he continues to innovate in the field of drug delivery systems. His work has been instrumental in advancing the applications of hyaluronan in medical treatments.

Collaborations

He has collaborated with notable professionals in his field, including Charles H Sherwood and Khalid K Sadozai. These collaborations have further enhanced the impact of his inventions.

Conclusion

Paul C A Bulpitt is a distinguished inventor whose work in hyaluronan derivatives has the potential to revolutionize drug delivery systems. His contributions are significant in the fields of ophthalmic surgery and tissue engineering.