Company Filing History:
Years Active: 2003-2006
Title: Paul Barstad: Innovator in Thiopurine Methyltransferase Activity Determination
Introduction
Paul Barstad is a notable inventor based in Hamilton, MT (US). He has made significant contributions to the field of medical diagnostics, particularly in the determination of thiopurine methyltransferase (TPMT) activity. With a total of 2 patents, Barstad's work is essential for improving patient care in inflammatory bowel disease.
Latest Patents
Barstad's latest patent focuses on a method for determining TPMT activity in subjects. This innovative method involves several steps, including reacting a sample obtained from the subject with a thiopurine derivative that is not 6-mercaptopurine. The process produces a methylated purine product, which is then analyzed to indicate the level of TPMT activity. The method is particularly useful for patients suffering from inflammatory bowel disease. The use of perchloric acid for precipitating proteinaceous material and the detection of the methylated purine product through fluorescence and high-performance liquid chromatography (HPLC) are key features of this invention.
Career Highlights
Barstad is associated with Prometheus Laboratories Inc., where he continues to develop and refine his innovative methods. His work has the potential to significantly impact the way TPMT activity is assessed, leading to better treatment options for patients.
Conclusion
Paul Barstad's contributions to the field of medical diagnostics through his patents on TPMT activity determination highlight his role as an important inventor. His innovative methods are paving the way for advancements in patient care and treatment strategies.