Company Filing History:
7 out of 21,594 
2 out of 92 
1 out of 170 
Years Active: 1989-2002
Title: Paul B Contestable: Innovator in Binding Assays
Introduction
Paul B Contestable is a notable inventor based in Rochester, NY (US). He has made significant contributions to the field of binding assays, holding a total of 10 patents. His work has advanced the understanding and application of specific binding ligands in various scientific contexts.
Latest Patents
Among his latest patents is a method for creating reduced cortisol conjugates. This innovative approach involves a specific binding assay that utilizes an enzyme inhibitor and an anti-inhibitor. The assay is designed to detect specific binding ligands through an immobilized receptor for the ligand, an immobilized reporter enzyme, an inhibitor antibody, and a water-soluble conjugate of the ligand and an anti-inhibitor antibody. The unique aspect of this assay is that both antibodies are specific for the reporter enzyme, yet they influence enzymatic activity in different ways. The inhibitor antibody effectively shuts down the activity of the reporter enzyme when complexed, while the anti-inhibitor antibody binds to the reporter enzyme without affecting its activity, thus preventing the binding of the inhibitor enzyme. This innovative assay provides a direct correlation between the generated signal and the target specific binding ligand.
Career Highlights
Throughout his career, Paul B Contestable has worked with prominent companies such as Eastman Kodak Company and Johnson & Johnson Clinical Diagnostics, Inc. His experience in these organizations has allowed him to refine his skills and contribute to groundbreaking innovations in the field.
Collaborations
Paul has collaborated with notable coworkers, including Brian A Snyder and Bradley P Boyer. These partnerships have further enriched his work and expanded the impact of his inventions.
Conclusion
Paul B Contestable is a distinguished inventor whose work in binding assays has led to significant advancements in the field. His innovative patents and collaborations with leading companies and professionals highlight his contributions to science and technology.