This inventor holds 128 USPTO granted patents and 19 published patent applications, plus 8 CIPO patents and 19 EPO patents, primarily in Heart Valve Technology (CPC class A61F2-2418). Top assignees: Mitral Valve Technologies Sarl, Origin Medsystems, Inc., Mitralign, Inc.. Active years: 1999-2026.
Inventors with similar research interests:
Location History:
- Irvine, CA (US) (2018)
- Louisville, KY (US) (1999 - 2024)
Company Filing History:
26 out of 26 
18 out of 179 
13 out of 37 
Years Active: 1999-2026
Areas of Expertise:
Paul A. Spence is a well-known inventor with an impressive collection of patents and a passion for developing new medical devices. Based in Louisville, KY in the US, Mr. Spence has obtained around 100 patents throughout his career, with many of his latest patents focused on providing effective solutions for mitral valve repair and replacement.
One of his recent inventions, an implant and method for repairing or replacing the functionality of the native mitral valve, has the potential to reduce or eliminate mitral regurgitation and residual mitral valve leakage. This implant uses a coiled anchor to position a prosthetic valve in the native mitral valve of a heart. The anchor is designed with three turns, where the second and third turns are positioned in the left ventricle of the heart and around the leaflets of the native mitral valve. The first turn is separated from the native mitral valve, located in the left atrium of the heart. This new approach has the advantage of requiring only one turn of the coiled anchor in the left atrium, making the implantation easier and safer.
Mr. Spence has also been involved in the development of valve docking devices, systems and methods, which could be used to treat conditions such as vein valve insufficiency and deep vein thrombosis. His contributions to these projects were critical, and his coworkers, such as Warren P. Williamson, IV and Mark Steven Ortiz, have hailed him as an innovative and driven inventor with a wealth of knowledge and talent.
Throughout his career, Mr. Spence has been affiliated with companies such as Mitral Valve Technologies Sarl and Abiomed, Inc. His work with these companies has been instrumental in the development of new treatments for cardiovascular diseases, benefiting millions of patients worldwide.
Overall, Paul A. Spence's contributions to the field of medical devices are impressive, and his passion for innovation is apparent. His dedication to improving patient outcomes and developing new treatment options have positioned him as one of the most talented inventors of his generation.