Los Angeles, CA, United States of America

Paul A Sandford


Average Co-Inventor Count = 4.9

ph-index = 22

Forward Citations = 2,573(Granted Patents)


Company Filing History:


Years Active: 1994-2003

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23 patents (USPTO):Explore Patents

Title: Innovations and Contributions of Paul A. Sandford in Biocompatible Materials

Introduction

Paul A. Sandford, an accomplished inventor based in Los Angeles, CA, holds an impressive portfolio of 23 patents. Throughout his career, he has made significant advancements in the field of biocompatible materials, particularly focusing on crosslinkable polypeptides and drug delivery systems. His inventions hold great promise for various applications in medicine and biotechnology.

Latest Patents

Among his latest contributions, Sandford developed rapidly crosslinkable polypeptide compositions. These compositions can be achieved through the introduction of unsaturated groups into the polypeptide using amide, ester, or thioester linkages, streamlined by employing acrylic anhydride as a derivatizing agent. Remarkably, these modified proteins can crosslink to themselves rapidly without the need for external agents, forming solid gel materials in mere seconds. This innovation opens the door to a wide array of applications, including the encapsulation of living cells, creation of wound dressings, prevention of post-surgical adhesions, and effective gene delivery systems.

Another notable patent addresses macrocapsules made from crosslinkable polysaccharides and polycations. This invention introduces a new class of biocompatible materials capable of undergoing free radical polymerization under certain light sources. It encompasses methods for creating polymerizable microcapsules that can encapsulate biological materials, making advances in drug delivery systems and bioadhesives.

Career Highlights

Sandford has had a notable career with significant contributions in various organizations. He has worked with Vivorx Pharmaceuticals, Inc. and Vivorx, Inc., where he applied his expertise in developing biocompatible technologies. His innovations have not only bolstered the companies he worked for but also contributed to the broader field of biotechnology.

Collaborations

Throughout his career, Paul A. Sandford has collaborated with prominent figures in the industry, including Neil P. Desai and Patrick Soon-Shiong. These partnerships have fostered a rich exchange of ideas and innovations, leading to groundbreaking advancements in biocompatible materials and their application in healthcare.

Conclusion

Paul A. Sandford's work in the field of biocompatible materials showcases his innovative spirit and dedication to improving health and medicine. His contributions through various patents highlight the potential for crosslinkable polypeptides and microcapsules in medical applications, paving the way for future research and development in this vital area.

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