The Woodlands, TX, United States of America

Paul A Cossum


Average Co-Inventor Count = 5.0

ph-index = 1

Forward Citations = 18(Granted Patents)


Company Filing History:

goldMedal1 out of 832,680 
Other
 patents

Years Active: 2001

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1 patent (USPTO):Explore Patents

Title: Paul A Cossum: Innovator in Anti-Viral Oligonucleotides

Introduction

Paul A Cossum is a notable inventor based in The Woodlands, TX (US). He has made significant contributions to the field of molecular biology, particularly in the development of anti-viral therapies. His innovative work focuses on guanosine-rich oligonucleotides, which have the potential to enhance treatment options for viral infections.

Latest Patents

Cossum holds a patent for "Anti-viral guanosine-rich tetrad forming oligonucleotides." This patent describes guanosine-rich oligonucleotides that favor the formation of a stable four-stranded structure under physiological conditions. These structures contain two stacked guanosine quartets (G4s) and demonstrate enhanced nuclease resistance, cellular uptake, and biological efficacy. The patent also outlines methods and compositions for treating viral infections using these oligonucleotides. Certain embodiments of the oligonucleotides are 16-17 nucleotides long and include at least one C-5 propynyl dU substitution. Additionally, a method for designing anti-viral oligonucleotides is disclosed.

Career Highlights

Throughout his career, Cossum has focused on advancing the understanding and application of oligonucleotides in therapeutic settings. His work has contributed to the development of innovative solutions for combating viral infections, showcasing his commitment to improving public health through scientific research.

Collaborations

Cossum has collaborated with notable colleagues, including Robert F Rando and Joshua O Ojwaug. These partnerships have likely enriched his research and contributed to the successful development of his patented technologies.

Conclusion

Paul A Cossum is a distinguished inventor whose work in anti-viral guanosine-rich oligonucleotides represents a significant advancement in the field of molecular biology. His innovative approaches have the potential to lead to more effective treatments for viral infections, highlighting the importance of continued research and development in this area.

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