Edison, NJ, United States of America

Patrick J Doherty


Average Co-Inventor Count = 3.0

ph-index = 2

Forward Citations = 9(Granted Patents)


Company Filing History:


Years Active: 1992-1995

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4 patents (USPTO):Explore Patents

Title: The Innovations of Patrick J. Doherty

Introduction

Patrick J. Doherty is a notable inventor based in Edison, NJ (US). He holds a total of four patents, showcasing his contributions to the field of biochemistry and pharmacology. His work primarily focuses on the development of novel compounds with significant applications in antiparasitic and insecticidal agents.

Latest Patents

Doherty's latest patents include "Bioconversion products of 27-hydroxy avermectin" and "Process for the glycosylation of avermectin compounds." The first patent discloses novel compounds derived from 22,23-dihydro avermectin B1 aglycone. These compounds are isomers of the 27-hydroxy adduct of the substrate avermectin compound, which have been glycosylated at the 4' position to yield 4'-O-glucosyl 27-OH avermectin compounds. These compounds and their intermediates are recognized for their high potency as antiparasitic, insecticidal, and anthelmintic agents. The second patent details a process where avermectin compounds are glycosylated at the 4' and 4'-positions by adding them to the fermentation medium of Saccharapolyspora erythrea. This process involves glycosylating the outer oleandrose sugar group of the avermectin compound with a glucose group, along with other modifications to the avermectin moiety.

Career Highlights

Patrick J. Doherty is currently associated with Merck & Company, Inc., a leading global healthcare company. His work at Merck has allowed him to contribute significantly to advancements in pharmaceutical sciences.

Collaborations

Throughout his career, Doherty has collaborated with notable colleagues such as Byron H. Arison and Marvin D. Schulman. These collaborations have further enhanced the impact of his innovative work in the field.

Conclusion

Patrick J. Doherty's contributions to the field of biochemistry through his patents and collaborations highlight his role as a significant inventor. His work continues to influence the development of effective pharmaceutical agents.

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