Patrick Havlik

Title: Patrick Havlik: Innovator in Antibody-Evading Virus Vectors

Introduction

Patrick Havlik is a notable inventor based in Carrboro, NC (US). He has made significant contributions to the field of gene delivery through his innovative work on antibody-evading virus vectors. His research focuses on improving the efficacy of viral vectors used in gene therapy.

Latest Patents

Patrick Havlik holds a patent for "Methods and compositions for antibody-evading virus vectors." This patent provides details on AAV capsid proteins that include modifications in their amino acid sequences. The disclosure outlines virus vectors that incorporate these modified AAV capsid proteins. Additionally, it presents methods for administering these virus vectors and capsids to cells or subjects in vivo. The patent also discusses recombinant adeno-associated virus (rAAV) capsid proteins with amino acid substitutions that reduce reactivity to neutralizing antibodies, enhancing their potential as gene delivery vehicles.

Career Highlights

Throughout his career, Patrick has worked with esteemed institutions such as the University of North Carolina at Chapel Hill and the University of Florida Research Foundation. His work has contributed to advancements in the field of gene therapy and viral vector technology.

Collaborations

Patrick has collaborated with notable colleagues, including Aravind Asokan and Mavis Agbandje-McKenna. Their joint efforts have furthered research in the area of antibody-evading virus vectors.

Conclusion

Patrick Havlik's innovative work in developing antibody-evading virus vectors has the potential to significantly impact gene therapy. His contributions to the field are marked by his patent and collaborations with leading researchers.