La Plata, MD, United States of America

Patrick A Caruana


Average Co-Inventor Count = 3.0

ph-index = 1

Forward Citations = 3(Granted Patents)


Location History:

  • Waldorf, MD (US) (2012 - 2015)
  • LaPlata, MD (US) (2018)

Company Filing History:


Years Active: 2012-2018

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3 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Patrick A. Caruana

Introduction

Patrick A. Caruana is a notable inventor based in La Plata, MD (US). He has made significant contributions to the field of chemistry, particularly in the synthesis of azo compounds and other chemical intermediates. With a total of 3 patents to his name, Caruana's work showcases his expertise and innovative spirit.

Latest Patents

One of Caruana's latest patents is focused on the synthesis of an azo intermediate, specifically 5,5'-azobis(4-chloropyrimidine). This compound is recognized for its stability, as it does not decompose until reaching approximately 194° C. The synthesis involves the oxidative dimerization of 5-amino-4-pyrimidine, a water-soluble compound. The azo intermediate is formed in an aqueous solution, although it is substantially insoluble in water, leading to the formation of a slurry during the reaction. The isolation of the azo intermediate is achieved through filtration, and it exhibits marginal solubility in acetone. The yield of this process is at least 18%, and the use of an inexpensive oxidizing agent, such as bleach, along with moderate reaction conditions, makes this synthesis suitable for scaling up.

Another significant patent by Caruana is a single reaction vessel process for the synthesis of salts of DNP. This batch reactor process involves the synthesis of potassium 5,7-dinitro-[2,1,3]-benzoxadiazol-4-olate-3-oxide (KDNP) from 3-bromo-2,4,6-trinitroanisole (ETNA). The process includes adding BTNA to a reaction vessel containing potassium azide and water, followed by heating the mixture to 90° C. After cooling to room temperature, the final solution is agitated, and the precipitate KDNP product is recovered by filtration.

Career Highlights

Caruana is currently employed at the United States Navy, where he contributes his expertise in chemical synthesis. His work is instrumental in advancing the Navy's research and development efforts.

Collaborations

Throughout his career, Caruana has collaborated with notable colleagues, including Alfred G. Stern and Alex J. Zaita. These collaborations have further enriched his research and innovation in the field.

Conclusion

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