Patricia J Malin

Title: Patricia J Malin: Innovator in High-Throughput Screening Technology

Introduction

Patricia J Malin is a prominent inventor based in Palo Alto, CA (US). She has made significant contributions to the field of biotechnology, particularly in the development of high-throughput screening methods. With a total of 5 patents to her name, her work has advanced the capabilities of cellular analysis and drug discovery.

Latest Patents

Among her latest patents is a high-throughput screening method and apparatus. This innovative method involves placing cells on a substrate that defines a plurality of discrete microwells, achieving a well density of greater than about 100/cm. Each well contains fewer than about 1000 cells that have been exposed to a selected agent. The method determines the change in conductance in each well by applying a low-voltage, AC signal across a pair of electrodes placed in that well. This allows for synchronous measurement of conductance, enabling the monitoring of growth or metabolic activity of the cells contained in each well. Additionally, the patent discloses an apparatus designed to carry out this screening method.

Career Highlights

Throughout her career, Patricia has worked with notable companies such as Cellstat Technologies, Inc. and Oncotherapeutics. Her experience in these organizations has contributed to her expertise in the field of high-throughput screening technologies.

Collaborations

Patricia has collaborated with esteemed colleagues, including Kenneth R Wada and Peter J Dehlinger. These partnerships have further enriched her work and innovations in biotechnology.

Conclusion

Patricia J Malin's contributions to high-throughput screening technology have made a significant impact in the field of biotechnology. Her innovative methods and collaborative efforts continue to advance research and development in cellular analysis.