This inventor holds 2 USPTO granted patents. Top assignee: Vanderbilt University. Active years: 1997-2002.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 1997-2002
Title: Innovations in Breast Cancer Detection by Patrice S. Obermiller
Introduction
Patrice S. Obermiller is an accomplished inventor based in Nashville, TN (US). She has made significant contributions to the field of breast cancer research, particularly in the detection and diagnosis of pre-invasive breast cancer. With a total of 2 patents to her name, her work has the potential to impact the lives of many individuals facing this disease.
Latest Patents
Obermiller's latest patents focus on methods for detecting and diagnosing pre-invasive breast cancer. One of her notable inventions provides a method for identifying differentially expressed genes in early, pre-invasive breast cancer tissue. These differentially expressed genes serve as genetic markers that indicate the presence of pre-invasive cancerous tissues. The invention employs microscopically-directed tissue sampling techniques combined with differential display or differential screening of cDNA libraries to determine the differential expression of genes in the early stages of breast cancer. The confirmation of differential expression is achieved through RT-PCR, nuclease protection assays, and in-situ hybridization of ductal carcinoma in situ tissue RNA and control tissue RNA. Additionally, her invention includes a method for screening compounds that induce expression of the BRCA1 gene, which plays a crucial role in regulating cell growth in both normal and malignant mammary epithelial cells.
Career Highlights
Patrice S. Obermiller is affiliated with Vanderbilt University, where she continues her research and innovation in the field of breast cancer detection. Her work is characterized by a commitment to advancing medical science and improving patient outcomes.
Collaborations
Obermiller has collaborated with notable colleagues, including Jeffrey T. Holt and David L. Page, further enhancing the impact of her research through teamwork and shared expertise.
Conclusion
Patrice S. Obermiller's innovative approaches to breast cancer detection exemplify the vital role of inventors in advancing medical technology. Her contributions are paving the way for improved diagnostic methods that could save lives.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile