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For the Inventor, By the Inventor

Milan, Italy

Pasqua Anna Oreste

USPTO Granted Patents = 13 

 

Average Co-Inventor Count = 2.4

ph-index = 5

Forward Citations = 94(Granted Patents)


Location History:

  • Milano, IT (2006)
  • Milan, IT (1992 - 2016)

Company Filing History:

goldMedal6 out of 6 
 
Glycores 2000 S.r.l.
 patents
silverMedal3 out of 17 
 
Inalco S.p.a.
 patents
bronzeMedal1 out of 44 
 
Sanofi Sa
 patents
4. 1 out of 6 
 
Ibsa Institut Biochimique Sa
 patents
5. 1 out of 15 
 
Fondazione Centro San Raffaele Del Monte Tabor
 patents
6. 2 out of 832,891 
Other
 patents
where one patent can have more than one assignee

Years Active: 1992-2016

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13 patents (USPTO):Explore Patents
1. 9346893 - Process for the preparation of highly O-sulfated, epimerized derivatives of K5 polysacchride and intermediates therein (2016-05-24),
2. 8513407 - Process for the preparation of N-acyl-(epi)K5-amine-O-sulfate-derivatives and products thus obtained (2013-08-20),
3. 8227449 - Glycosaminoglycans derived from K5 polysaccharide having high anticoagulant and antithrombotic activities and process for their preparation (2012-07-24),
4. 8193166 - Epimerized derivatives of K5 polysaccharide with a very high degree of sulfation (2012-06-05),
5. 7838644 - Epimerized derivatives of K5 polysaccharide with a very high degree of sulfation (2010-11-23),
6. 7812151 - Low molecular weight polysaccharides having antithrombotic activity (2010-10-12),
7. 7268122 - Use of oversulfated polysaccharides as inhibitors of HIV (2007-09-11),
8. 6992183 - Highly sulfated derivatives of K5 polysaccharide and their preparation (2006-01-31),
9. 6777398 - Process for the preparation of chondroitin sulfates from K4 polysaccharide and obtained products (2004-08-17),
10. 6288044 - O-sulfated bacterial polysaccharides (2001-09-11),
11. 6162797 - Derivatives of K5 polysaccharide having high anticoagulant activity (2000-12-19),
12. 5958899 - Polysaccharides having a high iduronic acid content (1999-09-28),
13. 5110918 - Process for preparing EDTA-free heparins, heparin fractions and fragments (1992-05-05),

Title: Pasqua Anna Oreste: Innovator in Polysaccharide Derivatives

Introduction

Pasqua Anna Oreste is a prominent inventor based in Milan, Italy, known for her significant contributions to the field of polysaccharide derivatives. With a total of 13 patents to her name, she has made remarkable advancements in the preparation of highly sulfated derivatives that have applications in both the cosmetic and pharmaceutical industries.

Latest Patents

Among her latest patents is a process for the preparation of highly O-sulfated, epimerized derivatives of K5 polysaccharide and intermediates therein. This innovative method describes the oversulfation of epiK5-N-sulfate to produce an epiK5-amine-O-oversulfate with a very high degree of sulfation. This compound is essentially free of activity on coagulation parameters, making it useful in cosmetic and pharmaceutical applications. Additionally, she has developed new low molecular weight epiK5-N-sulfates that serve as intermediates for the preparation of corresponding LMW-epiK5-N,O-oversulfate-derivatives.

Another notable patent involves the preparation of N-acyl-(epi)K5-amine-O-sulfate-derivatives and the products derived from this process. This method outlines the oversulfation of (epi)K5-N-sulfates to yield (epi)K5-amine-O-oversulfates with an extremely high degree of sulfation. These intermediates can be transformed into new N-acyl-(epi)K5-amine-O-oversulfates, which are also free of activity on coagulation parameters and beneficial in the cosmetic and pharmaceutical fields.

Career Highlights

Pasqua has worked with several companies throughout her career, including Glycores 2000 S.r.l. and Inalco S.p.a. Her work has significantly impacted the development of new products in her field, showcasing her expertise and innovative spirit.

Collaborations

Throughout her career, Pasqua has collaborated with notable professionals, including Giorgio Zoppetti and Giovanni Cipolletti. These partnerships have contributed to her success and the advancement of her research.

Conclusion

Pasqua Anna Oreste stands out as a leading inventor in the realm of polysaccharide derivatives, with her patents paving the way for new advancements in the cosmetic and pharmaceutical industries. Her innovative methods and collaborative efforts continue to

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