Location History:
- Los Angeles, CA (US) (2009 - 2011)
- Agoura Hills, CA (US) (1998 - 2017)
- Agoura, CA (US) (2001 - 2020)
Company Filing History:
8 out of 8 
4 out of 1,627 
1 out of 1 Years Active: 1998-2020
Title: Parkash S Gill: Innovator in Cancer Therapeutics
Introduction
Parkash S Gill is a prominent inventor based in Agoura Hills, California. He has made significant contributions to the field of cancer therapeutics, holding a total of 16 patents. His work focuses on innovative approaches to target cancer cells and improve treatment outcomes.
Latest Patents
One of his latest patents involves antibodies that bind to cell surface GRP78. This application provides antibodies or antigen-binding fragments that target cell surface GRP78 expressed on tumor cells, tumor endothelial cells, and tumor-initiating cancer cells. These anti-GRP78 antibodies exhibit a high affinity for GRP78 and are less immunogenic compared to their unmodified parent antibodies in humans. They function to inhibit GRP78, attenuate PI3K signaling, and promote apoptosis in tumor cells while leaving normal cells unaffected. This innovation is particularly useful for UPR-targeted cancer therapeutic treatments.
Another significant patent by Gill includes polypeptide compounds for inhibiting angiogenesis and tumor growth. This invention provides polypeptide compositions, including modified polypeptides, and methods for inhibiting Ephrin B2 or EphB4 activity. Additionally, it offers methods and compositions for treating cancer or angiogenesis-associated diseases.
Career Highlights
Throughout his career, Parkash S Gill has worked with notable organizations such as Vasgene Therapeutics, Inc. and the University of Southern California. His expertise and innovative mindset have positioned him as a key figure in the development of cancer therapies.
Collaborations
Gill has collaborated with esteemed colleagues, including Valery Krasnoperov and Ramachandra Reddy. These partnerships have further enhanced his research and contributions to the field.
Conclusion
Parkash S Gill's work in cancer therapeutics exemplifies the impact of innovative thinking in medicine. His patents and collaborations continue to pave the way for advancements in cancer treatment.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.