Company Filing History:
Years Active: 2013-2019
Title: Paola Picotti: Innovator in Protein Conformation Analysis
Introduction
Paola Picotti is a distinguished inventor based in Zurich, Switzerland. She has made significant contributions to the field of protein analysis, particularly in understanding protein conformations and developing high-throughput assays. With a total of 2 patents, her work has implications for various applications in biochemistry and molecular biology.
Latest Patents
Picotti's latest patents include a method for the determination of conformation and conformational changes of proteins and derivatives thereof. This innovative method proposes a series of steps to detect the conformational state of a protein within a complex mixture. The process involves limited proteolysis, denaturation, complete fragmentation, and analytical analysis to determine characteristic fragments.
Another notable patent is her method for high-throughput peptide/protein assay generation. This invention outlines a systematic approach to create assays for proteins or peptides of interest, including the synthesis of candidate proteotypic peptides and their analysis through selected reaction monitoring (SRM). This method enhances throughput and allows for the absolute quantification of peptides and proteins at a low cost.
Career Highlights
Paola Picotti has worked at prestigious institutions such as ETH Zurich and Eidgenössische Technische Hochschule Zurich. Her research has focused on advancing techniques in protein analysis, contributing to the scientific community's understanding of protein behavior and interactions.
Collaborations
Throughout her career, Picotti has collaborated with notable colleagues, including Yuehan Feng and Giorgia De Franceschi. These partnerships have fostered innovation and have been instrumental in her research endeavors.
Conclusion
Paola Picotti's contributions to the field of protein analysis through her innovative patents and collaborations highlight her role as a leading inventor. Her work continues to influence the scientific community and advance our understanding of protein dynamics.
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