Location History:
- Cambridge, MA (US) (2022)
- Pittsburgh, PA (US) (2019 - 2024)
Company Filing History:
Years Active: 2019-2024
Title: Paola Grandi: Innovator in Cancer Treatment
Introduction
Paola Grandi is a prominent inventor based in Pittsburgh, PA (US), known for her groundbreaking work in cancer treatment. With a total of 6 patents, she has made significant contributions to the field of oncolytic virotherapy, focusing on the use of modified viruses to target and destroy cancer cells.
Latest Patents
One of her latest patents involves a recombinant oncolytic Herpes Simplex Virus (oHSV) that includes a non-HSV ligand specific for molecules present on the surface of cancer cells. This invention aims to enhance the effectiveness of the virus in killing tumor cells while minimizing damage to non-cancerous cells. Another notable patent describes a recombinant viral vector that expresses a NKG2D activating ligand, which sensitizes cancer cells to attack by cytotoxic immune cells. This innovative approach allows for selective targeting of cancer cells, particularly gliomas such as glioblastoma, while reducing cytotoxicity towards healthy cells.
Career Highlights
Throughout her career, Paola has worked with esteemed institutions, including the University of Pittsburgh. Her research has focused on developing novel therapeutic strategies to combat cancer, leveraging her expertise in virology and molecular biology.
Collaborations
Paola has collaborated with notable colleagues such as Joseph C. Glorioso III and Hiroaki Uchida, contributing to the advancement of cancer treatment technologies.
Conclusion
Paola Grandi's innovative work in the field of cancer treatment exemplifies the potential of oncolytic viruses in modern medicine. Her contributions continue to pave the way for new therapeutic approaches that could significantly improve patient outcomes.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.