Location History:
- St. Louis, MO (US) (2022)
- Chesterfield, MO (US) (2015 - 2023)
Company Filing History:
7 out of 8 
2 out of 2 
1 out of 1 Years Active: 2015-2023
Title: The Innovative Contributions of Pamela T. Manning
Introduction
Pamela T. Manning, an accomplished inventor based in Chesterfield, Missouri, has made significant strides in the field of biotechnology. With ten patents to her name, her work primarily focuses on innovative therapeutic solutions aimed at addressing a variety of medical conditions.
Latest Patents
Among her notable inventions are therapeutic CD47 antibodies. These include anti-CD47 monoclonal antibodies with distinct functional profiles. These antibodies serve as therapeutics for preventing and treating solid and hematological cancers, ischemia-reperfusion injury, cardiovascular diseases, autoimmune diseases, and inflammatory diseases. The methodologies she developed for generating these anti-CD47 monoclonal antibodies are groundbreaking, as they also provide diagnostics for determining the level of CD47 in tissue samples. Furthermore, her inventions encompass antibody compounds that are effective in treating tissue ischemia and ischemic-reperfusion injury, as well as serving as anti-cancer agents that promote phagocytic uptake and clearance of susceptible cancer cells.
Career Highlights
Pamela has had an impressive career, having worked at notable companies such as Arch Oncology, Inc. and Tioma Therapeutics, Inc. Her contributions in these organizations have played a crucial role in advancing therapeutic options for patients dealing with serious health challenges.
Collaborations
Throughout her career, Pamela has collaborated with distinguished colleagues, including William A. Frazier and Gerhard Johann Frey. These partnerships have fostered a rich environment for innovation, allowing for the cross-pollination of ideas that can lead to groundbreaking advancements in healthcare.
Conclusion
Pamela T. Manning stands out as a prominent inventor who has made vital contributions to biotechnology. Her ten patents reflect a commitment to improving health outcomes through innovative therapeutic strategies. With her ongoing efforts and collaborations, she continues to push the boundaries of what is possible in the field of medicine.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.