Pamela Fink Charbonneau

Title: The Innovative Contributions of Pamela Fink Charbonneau

Introduction

Pamela Fink Charbonneau is a notable inventor based in New City, NY (US). She has made significant contributions to the field of biochemistry, particularly in the purification of capsular polysaccharides. Her innovative approach has led to advancements in the production processes that are crucial for various applications in medicine and biotechnology.

Latest Patents

Pamela holds 1 patent that describes a shortened process for producing a solution containing substantially purified capsular polysaccharides from a cellular lysate broth. The process involves ultrafiltering and diafiltering a clarified lysate, followed by pH adjustment to less than 4.5, which precipitates at least 98% of the protein in the solution without significantly affecting polysaccharide yield. Additionally, the method includes filtration using activated carbon to further purify the solution, ensuring that at least 90% of the remaining protein is removed while maintaining polysaccharide yield. The serotypes that can be purified using this process include 1, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F.

Career Highlights

Pamela has worked with Wyeth, a prominent company in the pharmaceutical industry. Her work has been instrumental in enhancing the efficiency of polysaccharide purification processes, which are vital for vaccine development and other medical applications.

Collaborations

Throughout her career, Pamela has collaborated with esteemed colleagues such as Yonghui Yuan and Mark Edward Ruppen. These collaborations have further enriched her research and contributed to the success of her innovative projects.

Conclusion

Pamela Fink Charbonneau's contributions to the field of biochemistry through her innovative patent demonstrate her commitment to advancing medical science. Her work continues to have a lasting impact on the industry, showcasing the importance of innovation in the development of effective medical solutions.