Location History:
- Brisbane, CA (US) (2020 - 2021)
- South San Francisco, CA (US) (2024)
Company Filing History:
Years Active: 2020-2024
Title: Pam Tsuruda: Innovator in Ophthalmic Treatments
Introduction
Pam Tsuruda is a prominent inventor based in Brisbane, CA (US). She has made significant contributions to the field of ophthalmology, particularly in developing methods to address age-related eye conditions. With a total of 3 patents, her work focuses on innovative solutions that target the underlying causes of vision loss.
Latest Patents
One of Pam Tsuruda's latest patents involves methods of inhibiting pathological angiogenesis. This invention is based on the discovery that many eye conditions associated with aging are mediated at least in part by cells bearing a senescent phenotype. Senescent cells accumulate with age and express factors that contribute to the pathophysiology of age-related conditions. The data show that in age-matched patients, the severity of age-related conditions correlates with the abundance of senescent cells, and that clearing senescent cells can help abrogate the condition. Small molecule drugs that remove senescent cells from affected tissue in the eye are provided, which have special efficacy in treating ophthalmic conditions. These drugs not only inhibit the progression of the disease but can also reverse some of the pathophysiology—such as neovascularization and vaso-obliteration—that lead to vision loss. These senolytic agents have an appropriate dose and specificity profile to be effective in the clinical management of previously intractable ophthalmic conditions.
Career Highlights
Pam Tsuruda is currently associated with Unity Biotechnology, Inc., where she continues to advance her research and innovations in the field of ophthalmology. Her work has garnered attention for its potential to significantly improve the quality of life for individuals suffering from age-related eye conditions.
Collaborations
Pam collaborates with notable colleagues, including Jill Hopkins and Harry Sweigard, who contribute to her research efforts and innovations.
Conclusion
Pam Tsuruda's innovative work in ophthalmic treatments showcases her dedication to addressing critical health issues related to aging. Her patents reflect a commitment to improving patient outcomes and advancing medical science.